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- Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals .
- Individualize dosing based on the severity of pain, patient response, prior analgesic experience, and risk factors for addiction, abuse, and misuse.
- Initial dose selection: consult conversion instructions.
- Each transdermal system is intended to be worn for 72 hours.
- Adhere to instructions concerning administration and disposal of DURAGESIC.
The possible side effects of DURAGESIC;
constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, abdominal pain, itching, redness, or rash where the patch is applied. Call your healthcare provider if you have any of these symptoms and they are severe.
- Mild to Moderate Hepatic and Renal Impairment: Initiate treatment with one half the usual starting dose, titrate slowly, and monitor for signs of respiratory and central nervous system depression.
Do not abruptly discontinue DURAGESIC in a physically-dependent patient
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Opioid non-tolerant patients.
Acute or intermittent pain, postoperative pain, mild pain.
Significant respiratory depression.
Acute or severe bronchial asthma in an unmonitored setting or in absence of resuscitative equipment. Known or suspected gastrointestinal obstruction, including paralytic ileus.
Known hypersensitivity to fentanyl or any of the components of the transdermal system.
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